Idiopathic Thrombocytopenic Purpura:

It is common in children and accounts for 90% of the pediatric cases of immunologic thrombocytopenia. The classic presentation of ITP is that of a previously healthy 1–4 yr old child who has the sudden onset of generalized petechiae and purpura. Often there is bleeding from the gums and mucous membrane, particularly with profound thrombocytopenia (platelet count < 10 × 109 /L). The two commonest differential diagnoses are aplastic anaemia and malignancy. The physical examination is normal other than the finding of petechiae and purpura. Splenomegaly is rare.