Retinoblastoma

Only about 10% of retinoblastomas are detected by routine ophthalmologic screening in the context of a positive family history. Overall, about 60% of cases are unilateral and nonhereditary, 15% unilateral and hereditary, and 25% bilateral and hereditary. Bilateral involvement is found in 42% of those presenting when younger than 1 yr of age but in only 21% of those presenting during 1 yr of age and is even less common at older ages of presentation.Retinoblastoma classically presents with leukocoria, a white pupillary reflex. Case like this is late presentation. Most unilateral disease presents as a large tumor. Enucleation is undertaken if there is no potential for useful vision.